卞坡，男，教授，博士生导师。2003年毕业于郑州大学，获凝聚态物理/辐射生物学方向博士学位。2003-2021年在中国科学院合肥物质科学院工作，2011年被聘为正高级研究员，博士生导师，2022年以东南学者三类人才引进英国正版365。目前为Frontiers in space technology 杂志编辑、大科学工程重离子加速器生物类评审专家、中国核学会射线束技术分会理事、 中国生物物理学会环境与辐射生物物理分会常务理事。

教育经历：

1999/09—2003/06   郑州大学    离子束生物工程重点实验室    博士 导师：霍裕平院士

1996/09—1999/06   郑州大学    离子束生物工程重点实验室    硕士 导师：霍裕平院士

1992/09—1996/06   郑州大学    物理学院                   本科                                                                                                          

研究工作经历：

2022/01—至今         英国上市公司365核医学教研室，教授, 博士生导师；

2011/03—2021/12  中科院合肥物质科学研究院，技术生物与农业工程研究所，

研究员，博士生导师；

2005/07—2011/2     中科院合肥物质科学研究院，技术生物与农业工程研究所,

副研究员，硕士生导师；

2003/07—2005/06   中科院合肥物质科学研究院，离子束院重点实验室,  博士后 合作导师：余增亮研究员

1. 国家重大科技专项-中国空间站空间科学与应用项目、HYZHXMH02002、2024.9-2028.8、主持；

2. 国家自然科学基金重点项目、12135016、2022.1-2026.12、主持；

3. 国家自然科学基金面上项目、12575357、2026.1-2029.12、主持；

4. 国家自然科学基金面上项目、12075275、2021.1-2024.12，主持；

5. 国家自然科学基金联合基金项目、U1732144、2018.1-2021.12、主持；

6. 国家自然科学基金联合基金项目、U1332127、2014.1-2017.12，主持；

7. 国家自然科学基金面上项目、11275230，2013.1-2017.12、主持；

8. 国家自然科学基金青年项目、10705029、2008.1-2011.12、主持；

9. 国家重点基础研究发展计划（973）、2014CB932002-4、子课题负责人；

1. Zhiyang Hou, Qiyi Yi, Mengying Wu, Lijun Wu, Fanghua Li, Ting Wang*, and Po Bian*. Assessment and Mitigation of CRISPR-Cas9-Induced Nontargeted Translocations. Advanced Science, 2025, 2414415.

2. Yufeng Zhang, Zelin Xu, Chen Wang, Jing Li, Mengying Wu, Qiyi Yi, Ting Wang, Po Bian*. Resveratrol attenuates prenatal X-ray-induced microcephaly and adult depression via SIRT1-mediated senescence suppression and TPH2/5-HT pathway restoration in mice. Phytomedicine, 2025,143:156845.

3. Liu Ding, Jingjing Zhang, Shanpeng Qiao, Jiyu Xu, Jing Li, Wenjing Zhang, Qiyi Yi, Yuejin Wu, Ting Wang*, and Po Bian*. The Effects of Feeding ybfQ-Deficient Gut Bacteria on Radio-Tolerance in Symbiotic Caenorhabditis elegans: The Key Role of Isoscoparin. Microorganisms 2025, 13, 2626.

4. Zhiyang Hou, Tianxiang Yu, Qiyi Yi, Yan Du, Libin Zhou, Ye Zhao, Yuejin Wu, Lijun Wu, Ting Wang* and Po Bian*. High-complexity of DNA double-strand breaks is key for alternative end-joining choice. Communications Biology, 2024, 7:936.

5. Lei Lv, Qinqin Wei, Jianxiao Zhang, Yitong Dong, Zhenglei Shan, Na Chang, Ye Zhao* , Po Bian* and Qiyi Yi*. IGF2BP3 prevent HMGB1 mRNA decay in bladder cancer and development. Cellular & Molecular Biology Letters, 2024, 29:39.

6. Qiyi Yi, Yujia Zhao, Ran Xia, Qinqin Wei, Fengmei Chao, Rui Zhang, Po Bian*, Lei Lv*. TRIM29 hypermethylation drives esophageal cancer progression via suppression of ZNF750. Cell Death Discovery, 2023, 9(191)

7. Liangwen Chen, Yun Wang, Xiuhong Zhou, Ting Wang, Huimin Zhan, Fei Wu, Haolan Li, Po Bian*, Zhongwen Xie*. Investigation into the communication between unheated and heat-stressed Caenorhabditis elegans via volatile stress signals. Scientific Reports, 2023, 24;13(1):3225. 

8. Zhangyu Dai, Wenjing Zhang, Mengke Shang, Huangqi Tang, Lijun Wu, Yuejin Wu, Ting Wang*, Po Bian*. A Non-Cell-Autonomous Mode of DNA Damage Response in Soma of Caenorhabditis elegans. International Journal of Molecular Sciences. 2022, 23(14): 7544.

9. Qiyi Yi, Youguang Pu, Fengmei Chao, Po Bian*, Lei Lv*. ACAP1 Deficiency Predicts Inferior Immunotherapy Response in Solid Tumors. Cancers, 2022, 14(23).

10. Huangqi Tang, Liangwen Chen, Zhangyu Dai, Wenjing Zhang, Ting Wang, Lijun Wu, Gaohong Wang, Po Bian*. Enhancement of DNA Damage Repair Potential in Germ Cells of Caenorhabditis elegans by a Volatile Signal from Their Irradiated Partners. DNA Repair, 2020,86:102755

11. Chenguang Deng, Jingjing Wu, Ting Wang, Gaohong Wang, Lijun Wu, Yuejin Wu, Po Bian*. Negative Modulation of Bystander DNA Repair Potential by X-ray-Targeted Tissue Volume of Arabidopsis thaliana. Radiation Research, 2019, 191:556-565.

12. Ting Wang, Jingjing Wu, Shaoxin Xu, Chenguang Deng, Lijun Wu, Yuejin Wu,  Po Bian*. A potential involvement of plant systemic response in initiating genotoxicity of Ag-nanoparticles in Arabidopsis thaliana. Ecotoxicology and Environmental Safety. 2019, 170:324-330.

13. Liangwen Chen, Huangqi Tang, Yan Du, Zhangyu Dan, Ting Wang, Lijun Wu, Libin Zhou*, Po Bian*. Induction of Reproductive Cell Death in Caenorhabditis elegans across Entire Linear-Energy-Transfer Range of Carbon-ion Irradiation. DNA Repair, 2018, 63: 39-46.

14. Ting Wang, Wei Xu, Huasheng Li, Chenguang Deng, Qiang Li, Yuejin Wu, Min Liu, Lijun Wu, Jinying Lu^*, Po Bian*. Effect of Modeled Microgravity on UV-C-induced Interplant Communication of Arabidopsis thaliana. Mutation Research, 2017, 806:1-8.

15. Chenguang Deng, Ting Wang, Jingjing Wu, Wei Xu, Xinghai Liu, Lijun Wu, Po Bian*. Modulation of Modeled Microgravity on Radiation-Induced Adaptive Response of Root Growth in Arabidopsis thaliana. Mutation Research, 2017, 796: 20–28.

16. Huangqi Tang, Liangwen Chen, Lianyun Chen, Bin Chen, Ting Wang, Furu Zhan, Lijun Wu, Po Bian*, Interaction between Radioadaptive Response and Radiation-Induced Bystander Effect in Caenorhabditis elegans: A Unique Role of the DNA Damage Checkpoint. Radiation Research, 2016, 186, 662-668.

17. Ting Wang, Wei Xu, Chenguang Deng, Shaoxin Xu, Fanghua Li,Yuejin Wu, Lijun Wu, Po Bian^*, A Pivotal Role of the Jasmonic Acid Signal Pathway in Mediating Radiation-induced Bystander Effects in Arabidopsis thaliana, Mutation Research, 2016, 791: 1-9.

18. Wei Xu, Ting Wang, Fanghua Li, Shaoxin Xu, Lijun Wu, Yuejin Wu, Po Bian*. UV-C–induced Alleviation of Tranional Gene Silence through Plant-plant Communication: Key Roles of Jasmonic Acid and Salicylic Acid Pathways. Mutation Research, 2016, 790: 56-67.

19. Huangqi Tang, Liangwen Chen, Jialu Liu, Jue Shi, Qingqing Li, Ting Wang, Lijun Wu, Furu Zhan*, Po Bian *. Radio-adaptive Response for Reproductive Cell Death Demonstrated in in vivo Tissue Model of Caenorhabditis elegans. Radiation Research, 2016, 185, 402-410.

20.  Wei Xu, Ting Wang, Shuyan Xu, Shaoxin Xu, Lijun Wu, Yuejin Wu and Po Bian*. Radiation-induced Bystander Epigenetic Effects demonstrated in Arabidopsis thaliana. Radiation Research. 183:511-524, 2015.

21.  Ting Wang, Qiao Sun, Wei Xu, Fanghua Li, Huasheng Li, Jinying Lu, Lijun Wu, Yuejin Wu, Min Liu* and Po Bian*. Modulation of Modeled Microgravity on Radiation-induced Bystander Responses in Arabidopsis thaliana, Mutation Research, 773:27-36, 2015.

22. Xiaoying Guo, Po Bian*, Junting Liang, Yichen Wang, Luzhi Li, Jun Wang, Hang Yuan, Shaopeng Chen, An Xu and Lijun Wu*. Synergistic Effects Induced by a Low Dose of Diesel Particulate Extract and Ultraviolet A in Caenorhabditis elegans: DNA Damage-Triggered Germ Cell Apoptosis. Chem. Res. Toxicol. 27(6): 990-1001, 2014.

23. Xiaoying Guo, Jie Sun, Po Bian*, Lianyun Chen, Furu Zhan, Jun Wang, An Xu, Yugang Wang, Tom K Hei, and Lijun Wu*. Radiation-Induced Bystander Signaling from Somatic Cells to Germ Cells in Caenorhabditis Elegans, Radiation Research, 180, 268-275, 2013.

24. Ting Wang, Fanghua Li, Qingfang Liu, Po Bian*, Jufang Wang, Yuejin Wu, Lijun Wu and Wenjian Li. Homologous Recombination in Arabidopsis Seeds along the Track of Energetic Carbon Ions, Mutation Research, 737, 51-57, 2012.

25. Ting Wang, Fanghua Li, Wei Xu, Po Bian*, Yuejin Wu and Lijun Wu. Novel features of radiation-induced bystander signaling in Arabidopsis thaliana demonstrated using root micro-grafting, Plant Signaling & Behavior, 7, 1566-1572, 2012.

26. Ting Wang, Fanghua Li, Shuyan Xu, Po Bian*, Yuejin Wu, Lijun Wu and Zengliang Yu. The time course of long-distance signaling in radiation-induced bystander effect in vivo in Arabidopsis Thaliana demonstrated using root micro-grafting, Radiation Research, 176, 234-243, 2011.

27. Fanghua Li, Ting Wang, Shuyan Xu, Hang Yuan, Po Bian*, Yuejin Wu, Lijun Wu and Zengliang Yu. Abscopal Mutagenic Effect of Low-energy-ions in Arabidopsis Thaliana Seeds, International Journal of Radiation Biology, 87, 984-992, 2011.

28.  Fanghua Li, Ping Liu, Ting Wang, Po Bian*, Yuejin Wu, Lijun Wu and Zengliang Yu. The Induction of Bystander Mutagenic Effects in vivo by alpha- irradiation in Whole Arabidopsis thaliana Plants, Radiation Research, 174, 228-237, 2010.

29. Fanghua Li, Ping Liu, Ting Wang, Po Bian*, Yuejin Wu, Lijun Wu and Zengliang Yu. Genotoxicity/mutagenicity of Formaldehyde Revealed by the Arabidopsis thaliana Plants Transgenic for Homologous Recombination Substrates, Mutation Research, 699, 35-43, 2010.